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Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15.
Nizi, Maria Giulia; Maksimainen, Mirko M; Murthy, Sudarshan; Massari, Serena; Alaviuhkola, Juho; Lippok, Barbara E; Sowa, Sven T; Galera-Prat, Albert; Prunskaite-Hyyryläinen, Renata; Lüscher, Bernhard; Korn, Patricia; Lehtiö, Lari; Tabarrini, Oriana.
Afiliación
  • Nizi MG; Department of Pharmaceutical Sciences, University of Perugia, 06123, Perugia, Italy.
  • Maksimainen MM; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Murthy S; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Massari S; Department of Pharmaceutical Sciences, University of Perugia, 06123, Perugia, Italy.
  • Alaviuhkola J; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Lippok BE; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, 52074, Aachen, Germany.
  • Sowa ST; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Galera-Prat A; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Prunskaite-Hyyryläinen R; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Lüscher B; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, 52074, Aachen, Germany.
  • Korn P; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, 52074, Aachen, Germany.
  • Lehtiö L; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland. Electronic address: lari.lehtio@oulu.fi.
  • Tabarrini O; Department of Pharmaceutical Sciences, University of Perugia, 06123, Perugia, Italy. Electronic address: oriana.tabarrini@unipg.it.
Eur J Med Chem ; 237: 114362, 2022 Jul 05.
Article en En | MEDLINE | ID: mdl-35500474
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poli(ADP-Ribosa) Polimerasas / ADP Ribosa Transferasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2022 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poli(ADP-Ribosa) Polimerasas / ADP Ribosa Transferasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2022 Tipo del documento: Article País de afiliación: Italia