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An effective strategy for ligand-mediated pulldown of the HER2/HER3/NRG1ß heterocomplex and cryo-EM structure determination at low sample concentrations.
Trenker, Raphael; Diwanji, Devan; Verba, Kliment A; Jura, Natalia.
Afiliación
  • Trenker R; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, United States.
  • Diwanji D; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, United States; Medical Scientist Training Program, University of California San Francisco, San Francisco, CA, United States.
  • Verba KA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, United States; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, United States. Electronic address: kliment.verba@ucsf.edu.
  • Jura N; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, United States; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, United States. Electronic address: natalia.jura@ucsf.edu.
Methods Enzymol ; 667: 633-662, 2022.
Article en En | MEDLINE | ID: mdl-35525557
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor ErbB-3 Tipo de estudio: Guideline Límite: Female / Humans Idioma: En Revista: Methods Enzymol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptor ErbB-3 Tipo de estudio: Guideline Límite: Female / Humans Idioma: En Revista: Methods Enzymol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos