A novel reversible fluorescent probe for Cu2+ and S2-ions and imaging in living cells.
Methods Appl Fluoresc
; 10(3)2022 May 27.
Article
en En
| MEDLINE
| ID: mdl-35588725
ABSTRACT
A novel fluorescent probe TSOC (thiazole salicylaldehyde oxazole chlorinated) was synthesized based on benzothiazole conjugated olefinic bonds with salicylicaldehyde unit as fluorophore and a phenyl oxazole unit as bonding unit. The probe could reversibly detect of Cu2+and S2-over other common ions with longer emission and large stokes shift in an aqueous solution at pH 7.3 (DMSO-Hepes, v/v, 51, 10 mM). The bonding mechanism was supported through the titration experiment of fluorescence and absorption spectroscopy,1H-NMR titration, HR-MS and DFT calculations. Moreover, the probe further exhibited good cell permeability and were successfully used to visualize Cu2+and S2-in living cells.
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Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oxazoles
/
Colorantes Fluorescentes
Idioma:
En
Revista:
Methods Appl Fluoresc
Año:
2022
Tipo del documento:
Article