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Cutaneous Involvement in Diseases with Plasma Cell Differentiation: Diagnostic Approach.
Zanelli, Magda; Palicelli, Andrea; Sanguedolce, Francesca; Zizzo, Maurizio; Filosa, Alessandra; Ricci, Linda; Cresta, Camilla; Martino, Giovanni; Bisagni, Alessandra; Zanetti, Eleonora; di Donato, Francesco; Melli, Beatrice; Soriano, Alessandra; Cimino, Luca; Cavazza, Alberto; Vivian, Lisa Francesca; Ascani, Stefano.
Afiliación
  • Zanelli M; Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Palicelli A; Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Sanguedolce F; Pathology Unit, Policlinico Riuniti, University of Foggia, 71122 Foggia, Italy.
  • Zizzo M; Surgical Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Filosa A; Section of Pathological Anatomy, United Hospitals Ancona, 60126 Ancona, Italy.
  • Ricci L; Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
  • Cresta C; Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
  • Martino G; Pathology Unit, Azienda Ospedaliera Santa Maria di Terni, University of Perugia, 05100 Terni, Italy.
  • Bisagni A; Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Zanetti E; Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • di Donato F; Department of Biomedical and Neuromotor Sciences, School of Anatomic Pathology, Bellaria Hospital, University of Bologna, 40126 Bologna, Italy.
  • Melli B; Department of Obstetrics and Gynaecology, Fertility Center, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Soriano A; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41124 Modena, Italy.
  • Cimino L; Gastroenterology Division, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Cavazza A; Department of Surgery, Medicine, Dentistry and Morphological Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.
  • Vivian LF; Ocular Immunology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
  • Ascani S; Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Curr Oncol ; 29(5): 3026-3043, 2022 04 24.
Article en En | MEDLINE | ID: mdl-35621636
Neoplasms with plasma cell differentiation may occasionally involve the skin. Cutaneous lesions may represent the first sign of an underlying systemic plasma cell malignancy, such as multiple myeloma, or the skin itself may be the primary site of occurrence of a hematological tumor with plasma cell differentiation. Starting from examples encountered in our daily practice, we discussed the diagnostic approach pathologists and clinicians should use when faced with cutaneous lesions with plasma cell differentiation. Cases of primary cutaneous marginal zone lymphoma, localized primary amyloidosis/amyloidoma, and cutaneous manifestations (secondary either to multiple myeloma or to plasmablastic lymphoma) are discussed, focusing on the importance of the adequate patient's work-up and precise clinicopathological correlation to get to the correct diagnosis and appropriate treatment. The pertinent literature has been reviewed, and the clinical presentation, pathological findings, main differential diagnoses, treatment, and outcome of neoplasms with plasma cell differentiation involving the skin are discussed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Hematológicas / Mieloma Múltiple Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Curr Oncol Año: 2022 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Hematológicas / Mieloma Múltiple Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Curr Oncol Año: 2022 Tipo del documento: Article País de afiliación: Italia
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