Inhibition of B-cell lymphoma 2 family proteins alters optical redox ratio, mitochondrial polarization, and cell energetics independent of cell state.

Gillette, Amani A; DeStefanis, Rebecca A; Pritzl, Stephanie L; Deming, Dustin A; Skala, Melissa C

Gillette, Amani A; DeStefanis, Rebecca A; Pritzl, Stephanie L; Deming, Dustin A; Skala, Melissa C.

Afiliación

Gillette AA; University of Wisconsin, Department of Biomedical Engineering, Madison, Wisconsin, United States.
DeStefanis RA; University of Wisconsin, McArdle Laboratory for Cancer Research, Department of Oncology, Madison, Wi, United States.
Pritzl SL; University of Wisconsin, Division of Hematology, Oncology and Palliative Care, Department of Medicin, United States.
Deming DA; University of Wisconsin, McArdle Laboratory for Cancer Research, Department of Oncology, Madison, Wi, United States.
Skala MC; University of Wisconsin, Division of Hematology, Oncology and Palliative Care, Department of Medicin, United States.

J Biomed Opt ; 27(5)2022 05.

Article en En | MEDLINE | ID: mdl-35643815

Asunto(s)

Flavina-Adenina Dinucleótido; NAD; Flavina-Adenina Dinucleótido/metabolismo; Mitocondrias/metabolismo; NAD/metabolismo; Oxidación-Reducción; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo

Palabras clave

autofluorescence; flavin adenine dinucleotide; mitochondria; nicotinamide adenine dinucleotide hydrogen; optical redox ratio

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavina-Adenina Dinucleótido / NAD Idioma: En Revista: J Biomed Opt Asunto de la revista: ENGENHARIA BIOMEDICA / OFTALMOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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