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Sustained Trem2 stabilization accelerates microglia heterogeneity and Aß pathology in a mouse model of Alzheimer's disease.
Dhandapani, Rahul; Neri, Marilisa; Bernhard, Mario; Brzak, Irena; Schweizer, Tatjana; Rudin, Stefan; Joller, Stefanie; Berth, Ramon; Kernen, Jasmin; Neuhaus, Anna; Waldt, Annick; Cuttat, Rachel; Naumann, Ulrike; Keller, Caroline Gubser; Roma, Guglielmo; Feuerbach, Dominik; Shimshek, Derya R; Neumann, Ulf; Gasparini, Fabrizio; Galimberti, Ivan.
Afiliación
  • Dhandapani R; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Neri M; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Bernhard M; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Brzak I; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Schweizer T; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Rudin S; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Joller S; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Berth R; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Kernen J; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Neuhaus A; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Waldt A; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Cuttat R; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Naumann U; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Keller CG; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Roma G; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Feuerbach D; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Shimshek DR; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Neumann U; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Gasparini F; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
  • Galimberti I; Department of Neuroscience, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland. Electronic address: ivan.galimberti@novartis.com.
Cell Rep ; 39(9): 110883, 2022 05 31.
Article en En | MEDLINE | ID: mdl-35649351
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Receptores Inmunológicos / Microglía / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Receptores Inmunológicos / Microglía / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Suiza