PDGF-BB-enriched collagen matrix to treat multiple gingival recessions with the tunneled coronally advanced flap.
Clin Adv Periodontics
; 12(4): 224-232, 2022 12.
Article
en En
| MEDLINE
| ID: mdl-35665500
ABSTRACT
BACKGROUND:
With technological advancements in reconstructive periodontology, traditional protocols for the treatment of gingival recessions (GRs) can be challenged. This manuscript presents preliminary findings of a novel minimally-invasive approach for the regenerative treatment of multiple adjacent GR defects.METHODS:
Two healthy adults were treated as part of this study. Multiple adjacent GRs in both subjects (1 in the mandible, and 1 in the maxilla) were treated employing a tunneled coronally advanced flap (TCAF) design, with the application of a cross-linked collagen matrix (CCM) that was enriched with recombinant human platelet-derived growth factor-BB (PDGF-BB) that was also applied on the prepared root surfaces. Clinical, ultrasonographic, esthetic, and patient-reported outcomes were observed at approximately 6- and 18-month time points.RESULTS:
All sites healed uneventfully after the treatments. Complete root coverage was achieved and maintained throughout the follow-up observations, from 6 to 18 months. Patients reported minimal discomfort and reduction of dentinal hypersensitivity at the augmented sites. The areas augmented with CCM + PDGF-BB revealed an increased soft tissue thickness relative to baseline (pretreatment) measures, as well as reduction in the level of the facial bone dehiscences.CONCLUSION:
This article describes the success of two cases of a novel minimally invasive regenerative approach for the treatment of multiple adjacent GR defects by the TCAF, using a CCM loaded with PDGF-BB. This approach offers potential as a minimally-invasive method to repair multiple adjacent GRs.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Becaplermina
/
Recesión Gingival
Tipo de estudio:
Guideline
Aspecto:
Patient_preference
Límite:
Adult
/
Humans
Idioma:
En
Revista:
Clin Adv Periodontics
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos