Doxorubicin-induced hepatic toxicity in rats: Mechanistic protective role of Omega-3 fatty acids through Nrf2/HO-1 activation and PI3K/Akt/GSK-3ß axis modulation.

Saleh, Dalia O; Mahmoud, Sawsan S; Hassan, Azza; Sanad, Eman F

Saleh, Dalia O; Mahmoud, Sawsan S; Hassan, Azza; Sanad, Eman F.

Afiliación

Saleh DO; Department of Pharmacology, Medical Research and Clinical Studies, National Research Centre, Giza, Egypt.
Mahmoud SS; Department of Pharmacology, Medical Research and Clinical Studies, National Research Centre, Giza, Egypt.
Hassan A; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Sanad EF; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Saudi J Biol Sci ; 29(7): 103308, 2022 Jul.

Article en En | MEDLINE | ID: mdl-35677895

Palabras clave

Doxorubicin; Glycogen synthase kinase-3ß; Hepatic toxicity; Nrf2 activation; Omega-3 fatty acids

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Saudi J Biol Sci Año: 2022 Tipo del documento: Article País de afiliación: Egipto

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