Evolved resistance to a novel cationic peptide antibiotic requires high mutation supply.

Santos-Lopez, Alfonso; Fritz, Melissa J; Lombardo, Jeffrey B; Burr, Ansen H P; Heinrich, Victoria A; Marshall, Christopher W; Cooper, Vaughn S

Santos-Lopez, Alfonso; Fritz, Melissa J; Lombardo, Jeffrey B; Burr, Ansen H P; Heinrich, Victoria A; Marshall, Christopher W; Cooper, Vaughn S.

Afiliación

Santos-Lopez A; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Fritz MJ; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Lombardo JB; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Burr AHP; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Heinrich VA; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Marshall CW; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.
Cooper VS; Department of Microbiology and Molecular Genetics, and Center for Evolutionary Biology and Medicine, University of Pittsburgh, Pittsburgh, PA, 15219 USA.

Evol Med Public Health ; 10(1): 266-276, 2022.

Article en En | MEDLINE | ID: mdl-35712084

Palabras clave

Acinetobacter baumannii; Pseudomonas aeruginosa; antimicrobial resistance; cationic peptide; mutation rate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Evol Med Public Health Año: 2022 Tipo del documento: Article