Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation.

Lindell, Robert B; Zhang, Donglan; Bush, Jenny; Wallace, Douglas C; Rabinowitz, Joshua D; Lu, Wenyun; Wherry, E John; Weiss, Scott L; Henrickson, Sarah E

Lindell, Robert B; Zhang, Donglan; Bush, Jenny; Wallace, Douglas C; Rabinowitz, Joshua D; Lu, Wenyun; Wherry, E John; Weiss, Scott L; Henrickson, Sarah E.

Afiliación

Lindell RB; Division of Critical Care Medicine, Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Zhang D; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Bush J; Pediatric Sepsis Program, Children's Hospital of Philadelphia, Philadelphia, PA.
Wallace DC; Division of Critical Care Medicine, Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Rabinowitz JD; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Lu W; Division of Critical Care Medicine, Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Wherry EJ; Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Weiss SL; Division of Human Genetics, Department of Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Henrickson SE; Department of Chemistry, Princeton University; Princeton, NJ.

Shock ; 57(6): 191-199, 2022 06 01.

Article en En | MEDLINE | ID: mdl-35759301

Asunto(s)

Leucocitos Mononucleares; Sepsis; Niño; Citocinas/metabolismo; Antígenos HLA-DR/metabolismo; Humanos; Leucocitos Mononucleares/metabolismo; Linfocitos/metabolismo; Masculino; Estudios Prospectivos; Proteómica; Factor de Necrosis Tumoral alfa

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 4_TD / 7_ODS3_muertes_prevenibles_nacidos_ninos Problema de salud: 2_muertes_prevenibles / 4_sepsis / 7_infections Asunto principal: Leucocitos Mononucleares / Sepsis Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Humans / Male Idioma: En Revista: Shock Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Panamá

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