Cepharanthine: A Promising Old Drug against SARS-CoV-2.
Adv Biol (Weinh)
; 6(12): e2200148, 2022 12.
Article
en En
| MEDLINE
| ID: mdl-35775953
ABSTRACT
Recently, the inhibiting effects of a clinically approved drug Cepharanthine on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have attracted widespread attention and discussion. However, the public does not understand the relevant research progress very well. This paper aims to introduce a brief history of studies on the effects of cepharanthine against SARS-CoV-2, including "discovery of anti-SARS-CoV-2 activity of cepharanthine in vitro", "potential mechanisms of cepharanthine against SARS-CoV-2", "confirmation of cepharanthine's anti-SARS-CoV-2 activity in vivo", "potential approaches for improving the druggability of cepharanthine" and "clinical trials of cepharanthine treating SARS-CoV-2 infection". Taken together, cepharanthine is believed to be a promising old drug for coronavirus disease-19 (COVID-19) therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bencilisoquinolinas
/
COVID-19
Límite:
Humans
Idioma:
En
Revista:
Adv Biol (Weinh)
Año:
2022
Tipo del documento:
Article
País de afiliación:
China