New synthesis of a late-stage tetracyclic key intermediate of lumateperone.

Milen, Mátyás; Nyulasi, Bálint; Nagy, Tamás; Simig, Gyula; Volk, Balázs

Milen, Mátyás; Nyulasi, Bálint; Nagy, Tamás; Simig, Gyula; Volk, Balázs.

Afiliación

Milen M; Egis Pharmaceuticals Plc., Directorate of Drug Substance Development, 1475 Budapest, P.O. Box 100, Hungary.
Nyulasi B; Egis Pharmaceuticals Plc., Directorate of Drug Substance Development, 1475 Budapest, P.O. Box 100, Hungary.
Nagy T; Egis Pharmaceuticals Plc., Directorate of Drug Substance Development, 1475 Budapest, P.O. Box 100, Hungary.
Simig G; Egis Pharmaceuticals Plc., Directorate of Drug Substance Development, 1475 Budapest, P.O. Box 100, Hungary.
Volk B; Egis Pharmaceuticals Plc., Directorate of Drug Substance Development, 1475 Budapest, P.O. Box 100, Hungary.

Beilstein J Org Chem ; 18: 653-659, 2022.

Article en En | MEDLINE | ID: mdl-35800146

Palabras clave

drug substance; indole synthesis; key intermediate; protecting group; telescoping

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Beilstein J Org Chem Año: 2022 Tipo del documento: Article País de afiliación: Hungria

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