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Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels.
Barbari, Stephanie R; Beach, Annette K; Markgren, Joel G; Parkash, Vimal; Moore, Elizabeth A; Johansson, Erik; Shcherbakova, Polina V.
Afiliación
  • Barbari SR; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Beach AK; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Markgren JG; Department of Medical Biochemistry and Biophysics, Umeå University, SE-90187 Umeå, Sweden.
  • Parkash V; Department of Medical Biochemistry and Biophysics, Umeå University, SE-90187 Umeå, Sweden.
  • Moore EA; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Johansson E; Department of Medical Biochemistry and Biophysics, Umeå University, SE-90187 Umeå, Sweden.
  • Shcherbakova PV; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Nucleic Acids Res ; 50(14): 8023-8040, 2022 08 12.
Article en En | MEDLINE | ID: mdl-35822874
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Saccharomyces cerevisiae / ADN Polimerasa II / Neoplasias / Nucleótidos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Saccharomyces cerevisiae / ADN Polimerasa II / Neoplasias / Nucleótidos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos