Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling.

Najafi, Sheyda; Barasa, Leonard; Huang, Sammy Y; Yoganathan, Sabesan; Perron, Jeanette C

Najafi, Sheyda; Barasa, Leonard; Huang, Sammy Y; Yoganathan, Sabesan; Perron, Jeanette C.

Afiliación

Najafi S; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Barasa L; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Huang SY; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA.
Yoganathan S; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA. yoganats@stjohns.edu.
Perron JC; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, USA. perronj@stjohns.edu.

Sci Rep ; 12(1): 12146, 2022 07 15.

Article en En | MEDLINE | ID: mdl-35840622

Asunto(s)

Bencimidazoles; Proteínas Smad; Bencimidazoles/farmacología; Proteína Morfogenética Ósea 2/metabolismo; Proteína Morfogenética Ósea 2/farmacología; Proteína Morfogenética Ósea 4/metabolismo; Proteína Morfogenética Ósea 7/metabolismo; Receptores de Proteínas Morfogenéticas Óseas; Proteínas Morfogenéticas Óseas/metabolismo; Proteínas Portadoras; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Smad/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bencimidazoles / Proteínas Smad Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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