Psychostimulant-induced aberrant DNA methylation in an in vitro model of human peripheral blood mononuclear cells.

Anier, Kaili; Somelar, Kelli; Jaako, Külli; Alttoa, Margret; Sikk, Kerli; Kokassaar, Raul; Kisand, Kai; Kalda, Anti

Anier, Kaili; Somelar, Kelli; Jaako, Külli; Alttoa, Margret; Sikk, Kerli; Kokassaar, Raul; Kisand, Kai; Kalda, Anti.

Afiliación

Anier K; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Somelar K; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia. kelli.somelar@ut.ee.
Jaako K; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Alttoa M; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Sikk K; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Kokassaar R; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Kisand K; Department of Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Kalda A; Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.

Clin Epigenetics ; 14(1): 89, 2022 07 16.

Article en En | MEDLINE | ID: mdl-35842682

Asunto(s)

Cocaína; Metilación de ADN; Animales; Cocaína/farmacología; ADN (Citosina-5-)-Metiltransferasas/genética; ADN (Citosina-5-)-Metiltransferasas/metabolismo; Metilasas de Modificación del ADN/genética; Decitabina/farmacología; Humanos; Interleucina-10/genética; Interleucina-6/genética; Leucocitos Mononucleares/metabolismo; Masculino; Ratones; ARN Mensajero/genética

Palabras clave

Amphetamine; Cocaine; DNA demethylation; DNA methylation; Decitabine; Human peripheral mononuclear cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cocaína / Metilación de ADN Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Clin Epigenetics Año: 2022 Tipo del documento: Article País de afiliación: Estonia

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