Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions.

Hensel, Jessica A; Nicholas, Sarah-Anne E; Kimble, Amy L; Nagpal, Arjun S; Omar, Omar M F; Tyburski, Jordan D; Jellison, Evan R; Ménoret, Antoine; Ozawa, Manabu; Rodriguez-Oquendo, Annabelle; Vella, Anthony T; Murphy, Patrick A

Hensel, Jessica A; Nicholas, Sarah-Anne E; Kimble, Amy L; Nagpal, Arjun S; Omar, Omar M F; Tyburski, Jordan D; Jellison, Evan R; Ménoret, Antoine; Ozawa, Manabu; Rodriguez-Oquendo, Annabelle; Vella, Anthony T; Murphy, Patrick A.

Afiliación

Hensel JA; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Nicholas SE; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Kimble AL; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Nagpal AS; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Omar OMF; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Tyburski JD; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Jellison ER; Department of Immunology, UConn Health, University of Connecticut, Farmington, CT 06030.
Ménoret A; Department of Immunology, UConn Health, University of Connecticut, Farmington, CT 06030.
Ozawa M; Institute of Medical Science, University of Tokyo, 113-8654 Tokyo, Japan.
Rodriguez-Oquendo A; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.
Vella AT; Department of Immunology, UConn Health, University of Connecticut, Farmington, CT 06030.
Murphy PA; Center for Vascular Biology, UConn Health, University of Connecticut, Farmington, CT 06030.

Proc Natl Acad Sci U S A ; 119(30): e2122227119, 2022 07 26.

Article en En | MEDLINE | ID: mdl-35858420

Asunto(s)

Aterosclerosis; Proteína de Unión al Tracto de Polipirimidina; Empalme Alternativo; Animales; Aterosclerosis/genética; Aterosclerosis/metabolismo; Endotelio/metabolismo; Ribonucleoproteínas Nucleares Heterogéneas/genética; Humanos; Inflamación/genética; Inflamación/metabolismo; Ratones; FN-kappa B/genética; FN-kappa B/metabolismo; Proteína de Unión al Tracto de Polipirimidina/genética; Proteína de Unión al Tracto de Polipirimidina/metabolismo

Palabras clave

alternative splicing; atherosclerosis; endothelial; inflammation; platelets

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína de Unión al Tracto de Polipirimidina / Aterosclerosis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article

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