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PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation.
Noone, Dylan P; Dijkstra, Douwe J; van der Klugt, Teun T; van Veelen, Peter A; de Ru, Arnoud H; Hensbergen, Paul J; Trouw, Leendert A; Sharp, Thomas H.
Afiliación
  • Noone DP; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
  • Dijkstra DJ; Department of Immunology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • van der Klugt TT; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
  • van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • de Ru AH; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Hensbergen PJ; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Trouw LA; Department of Immunology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
  • Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Proc Natl Acad Sci U S A ; 119(33): e2208144119, 2022 08 16.
Article en En | MEDLINE | ID: mdl-35939690
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína C-Reactiva / Componente Amiloide P Sérico / Activación de Complemento Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína C-Reactiva / Componente Amiloide P Sérico / Activación de Complemento Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos