Transcriptomes of Injured Lamprey Axon Tips: Single-Cell RNA-Seq Suggests Differential Involvement of MAPK Signaling Pathways in Axon Retraction and Regeneration after Spinal Cord Injury.

Jin, Li-Qing; Zhou, Yan; Li, Yue-Sheng; Zhang, Guixin; Hu, Jianli; Selzer, Michael E

Jin, Li-Qing; Zhou, Yan; Li, Yue-Sheng; Zhang, Guixin; Hu, Jianli; Selzer, Michael E.

Afiliación

Jin LQ; Shriners Hospitals Pediatric Research Center, The Lewis Katz School of Medicine (LKSOM) at Temple University, Philadelphia, PA 19140, USA.
Zhou Y; Department of Neural Sciences, Lewis Katz School of Medicine (LKSOM), 3500 North Broad Street, Philadelphia, PA 19140, USA.
Li YS; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Zhang G; DNA Sequence & Genomics Core Facility at the NHLBI, Bethesda, MD 20892, USA.
Hu J; Shriners Hospitals Pediatric Research Center, The Lewis Katz School of Medicine (LKSOM) at Temple University, Philadelphia, PA 19140, USA.
Selzer ME; Department of Neural Sciences, Lewis Katz School of Medicine (LKSOM), 3500 North Broad Street, Philadelphia, PA 19140, USA.

Cells ; 11(15)2022 07 27.

Article en En | MEDLINE | ID: mdl-35954164

Asunto(s)

Axones; Traumatismos de la Médula Espinal; Animales; Axones/metabolismo; Lampreas/genética; Mamíferos; Regeneración Nerviosa/genética; RNA-Seq; Transducción de Señal; Traumatismos de la Médula Espinal/genética; Traumatismos de la Médula Espinal/metabolismo; Transcriptoma/genética

Palabras clave

MAPK pathway; axon regeneration; circadian rhythm; local protein synthesis; single cell RNA-seq; spinal cord injury

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de la Médula Espinal / Axones Límite: Animals Idioma: En Revista: Cells Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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