Anti-Inflammatory Activity of 4-(4-(Heptyloxy)phenyl)-2,4-dihydro-3<i>H</i>-1,2,4-triazol-3-one via Repression of MAPK/NF-&#954;B Signaling Pathways in ß-Amyloid-Induced Alzheimer's Disease Models.

An, Fengmao; Xuan, Xinran; Liu, Zheng; Bian, Ming; Shen, Qingkun; Quan, Zheshan; Zhang, Guowei; Wei, Chengxi

Anti-Inflammatory Activity of 4-(4-(Heptyloxy)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one via Repression of MAPK/NF-κB Signaling Pathways in ß-Amyloid-Induced Alzheimer's Disease Models.

An, Fengmao; Xuan, Xinran; Liu, Zheng; Bian, Ming; Shen, Qingkun; Quan, Zheshan; Zhang, Guowei; Wei, Chengxi.

Afiliación

An F; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao 028000, China.
Xuan X; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao 028000, China.
Liu Z; Medical College, Inner Mongolia Minzu University, Tongliao 028000, China.
Bian M; First Clinical Medical College, Inner Mongolia Minzu University, Tongliao 028000, China.
Shen Q; College of Pharmacy, Yanbian University, Yanji 133002, China.
Quan Z; Institute of Pharmaceutical Chemistry and Pharmacology, Inner Mongolia Minzu University, Tongliao 028000, China.
Zhang G; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao 028000, China.
Wei C; Medical College, Inner Mongolia Minzu University, Tongliao 028000, China.

Molecules ; 27(15)2022 Aug 08.

Article en En | MEDLINE | ID: mdl-35956985

Asunto(s)

Enfermedad de Alzheimer; Enfermedades Neurodegenerativas; Fármacos Neuroprotectores; Enfermedad de Alzheimer/tratamiento farmacológico; Péptidos beta-Amiloides/metabolismo; Animales; Antiinflamatorios/farmacología; Sistema de Señalización de MAP Quinasas; FN-kappa B/metabolismo; Fármacos Neuroprotectores/farmacología; Ratas

Palabras clave

Alzheimer's disease; amyloid beta-peptides; mitogen-activated protein kinase/NF-kappa B signaling pathways; neuroinflammation; triazoles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos Neuroprotectores / Enfermedades Neurodegenerativas / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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