LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells.

Pan, Li; Chen, Xiang; Rassool, Feyruz Virgilia; Li, Chenglong; Lin, Jiayuh

Pan, Li; Chen, Xiang; Rassool, Feyruz Virgilia; Li, Chenglong; Lin, Jiayuh.

Afiliación

Pan L; Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Chen X; Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Rassool FV; Department of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.
Li C; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Lin J; Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA.

Biomedicines ; 10(8)2022 Aug 18.

Article en En | MEDLINE | ID: mdl-36009550

Palabras clave

IL-6 signaling pathway; STAT3; apoptosis; cell migration; small-molecule inhibitor; triple-negative breast cancer; tumor growth

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomedicines Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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