Your browser doesn't support javascript.
loading
Impact of sickle cell disease in shoulder arthroplasty: a matched cohort analysis.
Marigi, Erick M; Triplet, Jacob J; Alder, Kareme D; Cheema, Adnan; Sperling, John W; Sanchez-Sotelo, Joaquin.
Afiliación
  • Marigi EM; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Triplet JJ; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Alder KD; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Cheema A; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Sperling JW; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
  • Sanchez-Sotelo J; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address: sanchezsotelo.joaquin@mayo.edu.
J Shoulder Elbow Surg ; 32(2): 247-252, 2023 Feb.
Article en En | MEDLINE | ID: mdl-36115611
BACKGROUND: Sickle cell disease (SCD) is a genetic disorder of abnormal hemoglobin synthesis that is known to cause glenohumeral avascular necrosis (AVN). Little has been published on the use of shoulder arthroplasty (SA) for the treatment of glenohumeral AVN in SCD. We report on the clinical and radiographic results and postoperative complications following SA in the patient cohort. METHODS: A retrospective review was performed identifying 17 primary SAs (9 hemiarthroplasties, 7 anatomic total SAs, and 1 reverse total SA) in patients with a confirmed diagnosis of SCD and a minimum of 2-year follow-up. This cohort was matched (1:2) according to age, sex, body mass index, type of prosthesis, and year of surgery with patients who had undergone hemiarthroplasty or total SA for osteoarthritis (OA) or reverse total SA for cuff tear arthropathy. Outcomes included the visual analog scale (VAS) for pain, American Shoulder and Elbow Surgeons score, range of motion, and strength measurements in forward elevation (FE), external rotation (ER), and internal rotation (IR). RESULTS: Our cohort included 9 (52.9%) men with a mean age of 43 yr. The average follow-up time was 5.9 yr. In patients with SCD, SA provided significant improvements in VAS pain (9.1-3.8; P < .001), FE (95°-128°; P < .001), ER (24°-38°; P < .001), IR score (3.2-5.2; P < .001), FE strength (4.2-4.8; P < .001), ER strength (4.1-4.7; P < .001), IR strength (4.1-4.7; P < .001), and American Shoulder and Elbow Surgeons scores (48.6-73.5; P < .001). When compared to the matched cohort, the SCD group demonstrated higher preoperative (9.1 vs. 3.8; P < .001) and postoperative VAS scores (3.8 vs. 1.3; P < .001). Other clinical outcomes demonstrated no significant differences. There were 5 (29%) complications, 2 (11.8%) episodes of sickle cell crisis, and 3 (18%) reoperations in the SCD cohort. When compared to the matched cohort, there were no statistical differences with respect to complications (29% vs. 12%; P = .140) or reoperations (18% vs. 12%; P = .387). CONCLUSIONS: SA is an effective treatment modality for glenohumeral AVN in patients with SCD. Patients may expect improvements in pain, function, motion, and strength. However, final postoperative pain relief may be less than those treated with SA without SCD. Unique perioperative management is necessary to mitigate the risk of postoperative sickle cell crises.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Articulación del Hombro / Hemiartroplastia / Artroplastía de Reemplazo de Hombro / Anemia de Células Falciformes Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Shoulder Elbow Surg Asunto de la revista: ORTOPEDIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Articulación del Hombro / Hemiartroplastia / Artroplastía de Reemplazo de Hombro / Anemia de Células Falciformes Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Shoulder Elbow Surg Asunto de la revista: ORTOPEDIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
...