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Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1.
Leandro, João; Khamrui, Susmita; Suebsuwong, Chalada; Chen, Peng-Jen; Secor, Cody; Dodatko, Tetyana; Yu, Chunli; Sanchez, Roberto; DeVita, Robert J; Houten, Sander M; Lazarus, Michael B.
Afiliación
  • Leandro J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Khamrui S; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Suebsuwong C; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Chen PJ; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Secor C; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Dodatko T; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Yu C; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Sanchez R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • DeVita RJ; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Houten SM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Lazarus MB; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Open Biol ; 12(9): 220179, 2022 09.
Article en En | MEDLINE | ID: mdl-36128717

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sacaropina Deshidrogenasas / Lisina Límite: Animals / Humans Idioma: En Revista: Open Biol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sacaropina Deshidrogenasas / Lisina Límite: Animals / Humans Idioma: En Revista: Open Biol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
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