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Whole-genome sequence and assembly of the Javan gibbon (Hylobates moloch).
Escalona, Merly; VanCampen, Jake; Maurer, Nicholas W; Haukness, Marina; Okhovat, Mariam; Harris, Robert S; Watwood, Allison; Hartley, Gabrielle A; O'Neill, Rachel J; Medvedev, Paul; Makova, Kateryna D; Vollmers, Christopher; Carbone, Lucia; Green, Richard E.
Afiliación
  • Escalona M; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
  • VanCampen J; Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA.
  • Maurer NW; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
  • Haukness M; Department of Biomolecular Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
  • Okhovat M; University of California Santa Cruz Genomics Institute, Santa Cruz, CA 95064, USA.
  • Harris RS; Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA.
  • Watwood A; Department of Biology, Pennsylvania State University, University Park, PA, USA.
  • Hartley GA; Department of Biology, Pennsylvania State University, University Park, PA, USA.
  • O'Neill RJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06296, USA.
  • Medvedev P; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06296, USA.
  • Makova KD; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06296, USA.
  • Vollmers C; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06296, USA.
  • Carbone L; Center for Medical Genomics, Pennsylvania State University, University Park, PA, USA.
  • Green RE; Center for Computational Biology and Bioinformatics, Pennsylvania State University, University Park, PA, USA.
J Hered ; 114(1): 35-43, 2023 03 16.
Article en En | MEDLINE | ID: mdl-36146896
ABSTRACT
The Javan gibbon, Hylobates moloch, is an endangered gibbon species restricted to the forest remnants of western and central Java, Indonesia, and one of the rarest of the Hylobatidae family. Hylobatids consist of 4 genera (Holoock, Hylobates, Symphalangus, and Nomascus) that are characterized by different numbers of chromosomes, ranging from 38 to 52. The underlying cause of this karyotype plasticity is not entirely understood, at least in part, due to the limited availability of genomic data. Here we present the first scaffold-level assembly for H. moloch using a combination of whole-genome Illumina short reads, 10X Chromium linked reads, PacBio, and Oxford Nanopore long reads and proximity-ligation data. This Hylobates genome represents a valuable new resource for comparative genomics studies in primates.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma / Hylobates Límite: Animals País/Región como asunto: Asia Idioma: En Revista: J Hered Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma / Hylobates Límite: Animals País/Región como asunto: Asia Idioma: En Revista: J Hered Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
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