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Three new sesquiterpenes from Ixeris sonchifolia.
Tang, Meng; Tang, Shu-Han; Huang, Jin-Yue; Hattori, Masao; Zhang, Ning; Yang, Bo; Wu, Xiu-Hong; Zhang, Hai-Long; Wang, Zhi-Gang.
Afiliación
  • Tang M; Department of Pharmaceutical Analysis, College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
  • Tang SH; Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan.
  • Huang JY; Department of Clinical Pharmacy, Harbin Children Hospital, Harbin 150010, China.
  • Hattori M; Department of Pharmaceutical Analysis, College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
  • Zhang N; Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan.
  • Yang B; Department of Pharmaceutical Analysis, College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
  • Wu XH; Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan.
  • Zhang HL; Department of Pharmaceutical Analysis, College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
  • Wang ZG; Department of Pharmaceutical Analysis, College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
J Asian Nat Prod Res ; 25(6): 557-563, 2023 Jun.
Article en En | MEDLINE | ID: mdl-36173154
ABSTRACT
Two new guaiacene-type sesquiterpenes 13α-dihydroixerin acid, ixerin acid and one new secoguaiacene-type sesquiterpene secoixerin Z, along with four known compounds, were separated from ethanol extract of Ixeris sonchifolia. The structures were determined based on the detailed spectroscopic and physicochemical methods. The cytotoxic activity of the isolates was tested against A549 cells. Among them, compound 3 exhibited potent cytotoxicity against A549 cells with the IC50 of 5.6 ± 0.9 µM.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Asteraceae Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Asteraceae Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China