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N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells.
Nord, Joshua A; Wynia-Smith, Sarah L; Gehant, Alyssa L; Jones Lipinski, Rachel A; Naatz, Aaron; Rioja, Inmaculada; Prinjha, Rab K; Corbett, John A; Smith, Brian C.
Afiliación
  • Nord JA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Wynia-Smith SL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Gehant AL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Jones Lipinski RA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Naatz A; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Rioja I; Immuno-Epigenetics, Immunology Research Unit, GlaxoSmithKline Medicines Research Centre, Stevenage, United Kingdom.
  • Prinjha RK; Immuno-Epigenetics, Immunology Research Unit, GlaxoSmithKline Medicines Research Centre, Stevenage, United Kingdom.
  • Corbett JA; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
  • Smith BC; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.
Front Endocrinol (Lausanne) ; 13: 923925, 2022.
Article en En | MEDLINE | ID: mdl-36176467
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Proteínas Nucleares / Diabetes Mellitus Tipo 1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Proteínas Nucleares / Diabetes Mellitus Tipo 1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos