Engineering Cancer Selective Virotherapies: Are the Pieces of the Puzzle Falling into Place?

Swift, Emma A; Pollard, Steven M; Parker, Alan L

Swift, Emma A; Pollard, Steven M; Parker, Alan L.

Afiliación

Swift EA; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Pollard SM; Centre for Regenerative Medicine, Institute for Regeneration and Repair & Cancer Research UK Scotland Centre, University of Edinburgh, Edinburgh, United Kingdom.
Parker AL; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.

Hum Gene Ther ; 33(21-22): 1109-1120, 2022 11.

Article en En | MEDLINE | ID: mdl-36178346

Asunto(s)

Neoplasias; Viroterapia Oncolítica; Virus; Humanos; Vectores Genéticos/genética; Terapia Genética; Técnicas de Transferencia de Gen; Cápside; Virus/genética; Dependovirus/genética; Neoplasias/genética; Neoplasias/terapia

Palabras clave

AAV; adenovirus; cancer; capsid engineering; directed evolution; enhancer; gene therapy; immunotherapy; oncolytics; promoter; rational design; therapeutic payloads

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus / Viroterapia Oncolítica / Neoplasias Límite: Humans Idioma: En Revista: Hum Gene Ther Asunto de la revista: GENETICA MEDICA / TERAPEUTICA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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