Cell-Free DNA-Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial.

Neal, Richard D; Johnson, Peter; Clarke, Christina A; Hamilton, Stephanie A; Zhang, Nan; Kumar, Harpal; Swanton, Charles; Sasieni, Peter

Neal, Richard D; Johnson, Peter; Clarke, Christina A; Hamilton, Stephanie A; Zhang, Nan; Kumar, Harpal; Swanton, Charles; Sasieni, Peter.

Afiliación

Neal RD; Department of Health and Community Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter EX4 4PY, UK.
Johnson P; NHS England, London SE1 8UG, UK.
Clarke CA; GRAIL, LLC, a Subsidiary of Illumina, Inc., Menlo Park, CA 94025, USA.
Hamilton SA; GRAIL, LLC, a Subsidiary of Illumina, Inc., London, WC1V 7HP, UK.
Zhang N; GRAIL, LLC, a Subsidiary of Illumina, Inc., Menlo Park, CA 94025, USA.
Kumar H; GRAIL, LLC, a Subsidiary of Illumina, Inc., London, WC1V 7HP, UK.
Swanton C; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, WC1E 6DD, UK.
Sasieni P; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London NW1 1AT, UK.

Cancers (Basel) ; 14(19)2022 Oct 01.

Article en En | MEDLINE | ID: mdl-36230741

Palabras clave

cancer screening; cell-free nucleic acids; efficient design; liquid biopsy; multi-cancer early detection; population screening; randomised controlled trial

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 Problema de salud: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles Tipo de estudio: Clinical_trials / Diagnostic_studies / Risk_factors_studies / Screening_studies Idioma: En Revista: Cancers (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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