Cardiac innervations in diabetes mellitus-Anatomical evidence of neuropathy.
Anat Rec (Hoboken)
; 306(9): 2345-2365, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-36251628
ABSTRACT
The extensive innervations of the heart include a complex network of sympathetic, parasympathetic, and sensory nerves connected in loops that serve to regulate cardiac output. Metabolic dysfunction in diabetes affects many different organ systems, including the cardiovascular system; it causes cardiac arrhythmias, silent myocardial ischemia, and sudden cardiac death, among others. These conditions are associated with damage to the nerves that innervate the heart, cardiac autonomic neuropathy (CAN), which is caused by various pathophysiological mechanisms. In this review, the main facts about the anatomy of cardiac innervations and the current knowledge of CAN, its pathophysiological mechanisms, and its diagnostic approach are discussed. In addition, anatomical evidence for CAN from human and animal studies has been summarized.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus
/
Corazón
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Anat Rec (Hoboken)
Asunto de la revista:
ANATOMIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Croacia