Dynamics and observations of long-term orthodontic tooth movement and subsequent relapse in C57BL/6 mice.
Exp Anim
; 72(1): 103-111, 2023 Feb 21.
Article
en En
| MEDLINE
| ID: mdl-36261388
ABSTRACT
The risk of relapse associated with orthodontic treatment is a major problem. Despite extensive research and discussion regarding the risk of orthodontic relapse, the underlying mechanisms remain to be elucidated. This study aimed to evaluate relapse following orthodontic treatment in mice (C57BL/6) tested via the coil spring method based on tooth movement at 21 days and mechanical retention at 7 days after completion of the procedure. During the experiment, relapse was observed and evaluated over 7 days. At the end of orthodontic tooth movement, the average distance was 259.6 (± 10.9) µm, and tooth movement was observed in all mice. No significant differences in distance were observed at the end of the experimental treatment period or after 7 days of mechanical retention. The distance at the start of observation was 258.6 (± 10.4) µm, whereas that at the end was 155.4 (± 12.4) µm, indicating that the distance had decreased significantly. Relative to the total relapse distance over the 7-day period, 45.7 (± 4.3)% of the relapse was observed on Day 0-1. The mouse model established in the current study provides an effective and reproducible method for the optimal evaluation of relapse. Our findings clarified that most of the relapse occurs within 7 days during the initial observation stage.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Osteoclastos
/
Técnicas de Movimiento Dental
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Exp Anim
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
Japón