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An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas.
Lu, Xiaofan; Vano, Yann; Helleux, Alexandra; Su, Xiaoping; Lindner, Véronique; Davidson, Guillaume; Mouawad, Roger; Spano, Jean-Philippe; Rouprêt, Morgan; Elaidi, Reza; Compérat, Eva; Verkarre, Virginie; Sun, Chengming; Chevreau, Christine; Bennamoun, Mostefa; Lang, Hervé; Tricard, Thibault; Cheng, Wenxuan; Xu, Li; Davidson, Irwin; Yan, Fangrong; Fridman, Wolf Herman; Sautes-Fridman, Catherine; Oudard, Stéphane; Malouf, Gabriel G.
Afiliación
  • Lu X; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, Illkirch, France.
  • Vano Y; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Helleux A; Department of Medical Oncology, Hôpital Européen Georges Pompidou, Institut du Cancer Paris CARPEM, APHP, Université Paris Cité, Paris, France.
  • Su X; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, Illkirch, France.
  • Lindner V; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Davidson G; Department of Pathology, Strasbourg University Hospital, Strasbourg, France.
  • Mouawad R; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, Illkirch, France.
  • Spano JP; Department of Medical Oncology, Sorbonne University, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Rouprêt M; Department of Medical Oncology, Sorbonne University, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Elaidi R; Department of Urology, Sorbonne University, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Compérat E; Association pour la Recherche sur les Thérapeutiques Innovantes en Cancérologie, Paris, France.
  • Verkarre V; Department of Pathology, Sorbonne University, AP-HP, Hôpital Tenon, Paris, France.
  • Sun C; Department of Pathology, Hôpital Européen Georges Pompidou, Institut du Cancer Paris CARPEM, APHP, Université Paris Cité, Paris, France.
  • Chevreau C; Centre des Cordeliers, INSERM, Université de Paris Cité, Sorbonne Université, Paris, France.
  • Bennamoun M; Department of Medical Oncology, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France.
  • Lang H; Department of Medical Oncology, Institut Mutualiste Montsouris, Paris, France.
  • Tricard T; Department of Urology, Strasbourg University Hospital, Strasbourg, France.
  • Cheng W; Department of Urology, Strasbourg University Hospital, Strasbourg, France.
  • Xu L; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Davidson I; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Yan F; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, Illkirch, France.
  • Fridman WH; State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Sautes-Fridman C; Centre de Recherche des Cordeliers, INSERM, Université Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, Paris, France.
  • Oudard S; Centre de Recherche des Cordeliers, INSERM, Université Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, Paris, France.
  • Malouf GG; Department of Medical Oncology, Hôpital Européen Georges Pompidou, Institut du Cancer Paris CARPEM, APHP, Université Paris Cité, Paris, France.
Clin Cancer Res ; 29(7): 1279-1291, 2023 04 03.
Article en En | MEDLINE | ID: mdl-36374555
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_kidney_renal_pelvis_ureter_cancer Asunto principal: Carcinoma de Células Renales / Neoplasias Renales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_kidney_renal_pelvis_ureter_cancer Asunto principal: Carcinoma de Células Renales / Neoplasias Renales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Francia