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VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.
Sher, Steven; Whipp, Ethan; Walker, Janek; Zhang, Pu; Beaver, Larry; Williams, Katie; Orwick, Shelley; Ravikrishnan, Janani; Walker, Brandi; Perry, Elizabeth; Gregory, Charles; Purcell, Matthew; Pan, Alexander; Yan, Pearlly; Alinari, Lapo; Johnson, Amy J; Frigault, Melanie M; Greer, Joy M; Hamdy, Ahmed; Izumi, Raquel; Mo, Xiaokui; Sampath, Deepa; Woyach, Jennifer; Blachly, James; Byrd, John C; Lapalombella, Rosa.
Afiliación
  • Sher S; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Whipp E; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Walker J; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Zhang P; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Beaver L; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Williams K; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Orwick S; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Ravikrishnan J; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Walker B; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Perry E; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Gregory C; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Purcell M; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Pan A; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Yan P; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Alinari L; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Johnson AJ; Vincerx Pharma, Palo Alto, CA, USA.
  • Frigault MM; Vincerx Pharma, Palo Alto, CA, USA.
  • Greer JM; Vincerx Pharma, Palo Alto, CA, USA.
  • Hamdy A; Vincerx Pharma, Palo Alto, CA, USA.
  • Izumi R; Vincerx Pharma, Palo Alto, CA, USA.
  • Mo X; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Sampath D; Department of Hematopoietic Biology & Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Woyach J; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Blachly J; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Byrd JC; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. byrd2jc@ucmail.uc.edu.
  • Lapalombella R; Division of Hematology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA. rosa.lapalombella@osumc.edu.
Leukemia ; 37(2): 326-338, 2023 02.
Article en En | MEDLINE | ID: mdl-36376377

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Leucemia Linfocítica Crónica de Células B / Factor B de Elongación Transcripcional Positiva Límite: Animals Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Leucemia Linfocítica Crónica de Células B / Factor B de Elongación Transcripcional Positiva Límite: Animals Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
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