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Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity.
Crombie, Elisa M; Kim, Seonyoung; Adamson, Stuart; Dong, Han; Lu, Tzu-Chiao; Wu, Yiju; Wu, Yajun; Levy, Yotam; Stimple, Nolan; Lam, Wing Moon R; Hey, Hwee Weng D; Withers, Dominic J; Hsu, Ao-Lin; Bay, Boon Huat; Ochala, Julien; Tsai, Shih-Yin.
Afiliación
  • Crombie EM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Kim S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Adamson S; Buck Institute for Research on Aging, Novato, California, USA.
  • Dong H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Lu TC; Research Center for Healthy Aging, China Medical University, Taichung, Taiwan.
  • Wu Y; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Wu Y; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Levy Y; Centre of Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College, London, UK.
  • Stimple N; Buck Institute for Research on Aging, Novato, California, USA.
  • Lam WMR; Department of Orthopedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Hey HWD; Department of Orthopedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Withers DJ; Metabolic Signalling Group, Medical Research Council London Institute of Medical Sciences (LMS), London, UK.
  • Hsu AL; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Bay BH; Research Center for Healthy Aging, China Medical University, Taichung, Taiwan.
  • Ochala J; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Tsai SY; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
J Cachexia Sarcopenia Muscle ; 14(1): 198-213, 2023 02.
Article en En | MEDLINE | ID: mdl-36398408
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcopenia / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Animals Idioma: En Revista: J Cachexia Sarcopenia Muscle Año: 2023 Tipo del documento: Article País de afiliación: Singapur
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcopenia / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Animals Idioma: En Revista: J Cachexia Sarcopenia Muscle Año: 2023 Tipo del documento: Article País de afiliación: Singapur