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D-2HG comes out of its shell: Metabolic effects on the immune environment.
Schvartzman, Juan Manuel; Intlekofer, Andrew M.
Afiliación
  • Schvartzman JM; Division of Hematology & Oncology, Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: js5279@cumc.columbia.edu.
  • Intlekofer AM; Human Oncology & Pathogenesis Program and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: intlekoa@mskcc.org.
Mol Cell ; 82(23): 4407-4409, 2022 Dec 01.
Article en En | MEDLINE | ID: mdl-36459984
A recent study by Notarangelo et al.1 highlights the potential for tumor-derived D-2HG to inhibit neighboring T cell function through a novel mechanism.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article