Examining the cooperation between extrachromosomal DNA circles.

Zhang, Jiahui; Zhang, Cheng-Zhong

Zhang, Jiahui; Zhang, Cheng-Zhong.

Afiliación

Zhang J; Department of Data Science, Dana-Farber Cancer Institute, Boston, United States.
Zhang CZ; Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, United States.

Elife ; 112022 12 07.

Article en En | MEDLINE | ID: mdl-36476649

ABSTRACT

ABSTRACT

In a departure from previous findings, new results suggest that free-floating pieces of DNA which carry additional copies of cancer-driving genes do not tend to cluster or have increased transcription.

Asunto(s)

ADN; ADN/genética

Palabras clave

cancer; chromosomes; extrachromosomal DNA; gene expression; glioblastoma; human; oncogenes; super-resolution imaging; transcription factors hub

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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