ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized PINK1/Parkin-mediated mitophagy.

Lu, Chunfeng; Ge, Ting; Shao, Yunyun; Cui, Wenqian; Li, Zhe; Xu, Wenxuan; Bao, Xiaofeng

ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized PINK1/Parkin-mediated mitophagy.

Lu, Chunfeng; Ge, Ting; Shao, Yunyun; Cui, Wenqian; Li, Zhe; Xu, Wenxuan; Bao, Xiaofeng.

Afiliación

Lu C; School of Pharmacy, Nantong University, Nantong, China.
Ge T; School of Pharmacy, Nantong University, Nantong, China.
Shao Y; School of Pharmacy, Nantong University, Nantong, China.
Cui W; School of Pharmacy, Nantong University, Nantong, China.
Li Z; School of Pharmacy, Nantong University, Nantong, China.
Xu W; School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Bao X; School of Pharmacy, Nantong University, Nantong, China.

Cell Prolif ; 56(3): e13378, 2023 Mar.

Article en En | MEDLINE | ID: mdl-36514923

Asunto(s)

Hepatopatías Alcohólicas; Mitofagia; Ratones; Animales; Hepatocitos/metabolismo; Hepatopatías Alcohólicas/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Etanol; Proteínas Quinasas/metabolismo; ARN Interferente Pequeño/metabolismo; Senescencia Celular

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mitofagia / Hepatopatías Alcohólicas Límite: Animals Idioma: En Revista: Cell Prolif Año: 2023 Tipo del documento: Article País de afiliación: China

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