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[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
Murthy, Sudarshan; Nizi, Maria Giulia; Maksimainen, Mirko M; Massari, Serena; Alaviuhkola, Juho; Lippok, Barbara E; Vagaggini, Chiara; Sowa, Sven T; Galera-Prat, Albert; Ashok, Yashwanth; Venkannagari, Harikanth; Prunskaite-Hyyryläinen, Renata; Dreassi, Elena; Lüscher, Bernhard; Korn, Patricia; Tabarrini, Oriana; Lehtiö, Lari.
Afiliación
  • Murthy S; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Nizi MG; Department of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.
  • Maksimainen MM; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Massari S; Department of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.
  • Alaviuhkola J; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Lippok BE; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.
  • Vagaggini C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, SienaI-53100, Italy.
  • Sowa ST; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Galera-Prat A; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Ashok Y; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Venkannagari H; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Prunskaite-Hyyryläinen R; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
  • Dreassi E; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, SienaI-53100, Italy.
  • Lüscher B; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.
  • Korn P; Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Aachen52074, Germany.
  • Tabarrini O; Department of Pharmaceutical Sciences, University of Perugia, Perugia06123, Italy.
  • Lehtiö L; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu90220, Finland.
J Med Chem ; 66(2): 1301-1320, 2023 01 26.
Article en En | MEDLINE | ID: mdl-36598465
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tanquirasas / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Finlandia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tanquirasas / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Finlandia