Rheumatic Heart Disease: JACC Focus Seminar 2/4.
J Am Coll Cardiol
; 81(1): 81-94, 2023 01 03.
Article
en En
| MEDLINE
| ID: mdl-36599614
ABSTRACT
It is a sad reality that although eminently preventable, and despite possessing such knowledge for >70 years, rheumatic heart disease (RHD) remains the most common cause of cardiovascular morbidity and early mortality in young people worldwide. A disease of the poor, RHD is one of the most neglected diseases. Several challenges are unique to the acute rheumatic fever/RHD continuum and contribute to its persistence, including its sequestration among the poorest, its protracted natural history, the erratic availability of penicillin, and the lack of a concerted effort in endemic regions. However, there is cause for optimism following a resurgence in scientific interest over the last 15 years. This review presents the latest advancements in epidemiology, diagnosis, and management. It also discusses pressing research questions on disease pathophysiology, the barriers to implementation of effective management strategies, and pragmatic policy solutions required for translation of current knowledge into meaningful action.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
3_ND
/
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
2_enfermedades_transmissibles
/
3_neglected_diseases
/
6_cardiovascular_diseases
/
6_musculoskeletal_diseases_rheumatic_disorders
/
6_other_circulatory_diseases
Asunto principal:
Fiebre Reumática
/
Cardiopatía Reumática
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Humans
Idioma:
En
Revista:
J Am Coll Cardiol
Año:
2023
Tipo del documento:
Article