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Finding shortest and nearly shortest path nodes in large substantially incomplete networks by hyperbolic mapping.
Kitsak, Maksim; Ganin, Alexander; Elmokashfi, Ahmed; Cui, Hongzhu; Eisenberg, Daniel A; Alderson, David L; Korkin, Dmitry; Linkov, Igor.
Afiliación
  • Kitsak M; Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, 2600 GA, Delft, The Netherlands. maksim.kitsak@gmail.com.
  • Ganin A; Network Science Institute, Northeastern University, 177 Huntington avenue, Boston, MA, 022115, USA. maksim.kitsak@gmail.com.
  • Elmokashfi A; University of Virginia, Department of Systems and Information Engineering, Charlottesville, VA, 22904, USA.
  • Cui H; U.S. Army Engineer Research and Development Center, Contractor, Concord, MA, 01742, USA.
  • Eisenberg DA; Simula Metropolitan Center for Digital Engineering, Oslo, Norway.
  • Alderson DL; Bioinformatics and Computational Biology Program, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
  • Korkin D; Institute for Genomic Medicine, Columbia University Medical Center, New York, New York, USA.
  • Linkov I; Department of Operations Research, Naval Postgraduate School, Monterey, CA, 93943, USA.
Nat Commun ; 14(1): 186, 2023 01 17.
Article en En | MEDLINE | ID: mdl-36650144
Dynamic processes on networks, be it information transfer in the Internet, contagious spreading in a social network, or neural signaling, take place along shortest or nearly shortest paths. Computing shortest paths is a straightforward task when the network of interest is fully known, and there are a plethora of computational algorithms for this purpose. Unfortunately, our maps of most large networks are substantially incomplete due to either the highly dynamic nature of networks, or high cost of network measurements, or both, rendering traditional path finding methods inefficient. We find that shortest paths in large real networks, such as the network of protein-protein interactions and the Internet at the autonomous system level, are not random but are organized according to latent-geometric rules. If nodes of these networks are mapped to points in latent hyperbolic spaces, shortest paths in them align along geodesic curves connecting endpoint nodes. We find that this alignment is sufficiently strong to allow for the identification of shortest path nodes even in the case of substantially incomplete networks, where numbers of missing links exceed those of observable links. We demonstrate the utility of latent-geometric path finding in problems of cellular pathway reconstruction and communication security.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algoritmos / Transducción de Señal Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algoritmos / Transducción de Señal Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos
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