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Current Scenario of Clinical Cancer Research in Latin America and the Caribbean.
Gössling, Gustavo; Rebelatto, Taiane F; Villarreal-Garza, Cynthia; Ferrigno, Ana S; Bretel, Denisse; Sala, Raul; Giacomazzi, Juliana; William, William N; Werutsky, Gustavo.
Afiliación
  • Gössling G; Latin American Cooperative Oncology Group (LACOG), Porto Alegre 90619-900, RS, Brazil.
  • Rebelatto TF; Latin American Cooperative Oncology Group (LACOG), Porto Alegre 90619-900, RS, Brazil.
  • Villarreal-Garza C; Breast Cancer Center Hospital Zambrano Hellion TecSalud-Tecnologico de Monterrey, Monterrey 66278, NL, Mexico.
  • Ferrigno AS; Breast Cancer Center Hospital Zambrano Hellion TecSalud-Tecnologico de Monterrey, Monterrey 66278, NL, Mexico.
  • Bretel D; Grupo de Estudios Clínicos Oncológicos del Perú (GECO PERU), Lima 15038, Peru.
  • Sala R; Grupo Argentino de Investigación Clínica en Oncología (GAICO), Rosario S2124KBO, Argentina.
  • Giacomazzi J; Latin American Cooperative Oncology Group (LACOG), Porto Alegre 90619-900, RS, Brazil.
  • William WN; Hospital BP-Beneficência Portuguesa de São Paulo, São Paulo 01323-001, SP, Brazil.
  • Werutsky G; Latin American Cooperative Oncology Group (LACOG), Porto Alegre 90619-900, RS, Brazil.
Curr Oncol ; 30(1): 653-662, 2023 01 04.
Article en En | MEDLINE | ID: mdl-36661699
ABSTRACT
In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, including a lack of oncology clinical trials. In this article, we will introduce the current status of the region's clinical research in cancer, with a special focus on academic cancer research groups and investigator-initiated research (IIR) initiatives. Investigators in LAC have strived to improve cancer research despite drawbacks and difficulties in funding, regulatory timelines, and a skilled workforce. Progress has been observed in the representation of this region in clinical trial development and conduct, as well as in scientific productivity. However, most oncology trials in the region have been sponsored by pharmaceutical companies, highlighting the need for increased funding from governments and private foundations. Improvements in obtaining and/or strengthening the LAC cancer research group's financing will provide opportunities to address cancer therapies and management shortcomings specific to the region. Furthermore, by including this large, ethnic, and genetically diverse population in the world's research agenda, one may bridge the gap in knowledge regarding the applicability of results of clinical trials now mainly conducted in populations from the Northern Hemisphere.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Brasil
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