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Informative Censoring-A Cause of Bias in Estimating COVID-19 Mortality Using Hospital Data.
Lin, Hung-Mo; Liu, Sean T H; Levin, Matthew A; Williamson, John; Bouvier, Nicole M; Aberg, Judith A; Reich, David; Egorova, Natalia.
Afiliación
  • Lin HM; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Liu STH; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Levin MA; Department of Anesthesiology, Perioperative and Pain Medicine, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Williamson J; Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
  • Bouvier NM; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Aberg JA; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Reich D; Department of Anesthesiology, Perioperative and Pain Medicine, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Egorova N; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Life (Basel) ; 13(1)2023 Jan 11.
Article en En | MEDLINE | ID: mdl-36676159
ABSTRACT
(1)

Background:

Several retrospective observational analyzed treatment outcomes for COVID-19; (2)

Methods:

Inverse probability of censoring weighting (IPCW) was applied to correct for bias due to informative censoring in database of hospitalized patients who did and did not receive convalescent plasma; (3)

Results:

When compared with an IPCW analysis, overall mortality was overestimated using an unadjusted Kaplan-Meier curve, and hazard ratios for the older age group compared to the youngest were underestimated using the Cox proportional hazard models and 30-day mortality; (4)

Conclusions:

An IPCW analysis provided stabilizing weights by hospital admission.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Life (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Life (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos