Enhanced Immunomodulation, Anti-Apoptosis, and Improved Tear Dynamics of (PEG)-BHD1028, a Novel Adiponectin Receptor Agonist Peptide, for Treating Dry Eye Disease.

Lee, In-Kyung; Yoon, Kyung-Chul; Kang, Seong-Soo; Seon, Su-Kyung; Lee, Kwanghyun; Kim, Brian B

Lee, In-Kyung; Yoon, Kyung-Chul; Kang, Seong-Soo; Seon, Su-Kyung; Lee, Kwanghyun; Kim, Brian B.

Afiliación

Lee IK; EncuraGen, Inc., Anyang 14058, Republic of Korea.
Yoon KC; Department of Ophthalmology, Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju 61469, Republic of Korea.
Kang SS; Biomaterial R&BD Center, Chonnam National University, Gwangju 61186, Republic of Korea.
Seon SK; Biomaterial R&BD Center, Chonnam National University, Gwangju 61186, Republic of Korea.
Lee K; Department of Ophthalmology, National Health Insurance Service Ilsan Hospital, Goyang-si 10444, Republic of Korea.
Kim BB; EncuraGen, Inc., Anyang 14058, Republic of Korea.

Pharmaceutics ; 15(1)2022 Dec 26.

Article en En | MEDLINE | ID: mdl-36678707

Palabras clave

(PEG)-BHD1028; AdipoR1; AdipoR2; adiponectin; adiponectin receptors; anti-apoptosis; anti-inflammation; dry eye disease (DED); epithelial cell protection; peptide drug

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2022 Tipo del documento: Article