Therapeutic targeting of TEAD transcription factors in cancer.

Pobbati, Ajaybabu V; Kumar, Ramesh; Rubin, Brian P; Hong, Wanjin

Pobbati, Ajaybabu V; Kumar, Ramesh; Rubin, Brian P; Hong, Wanjin.

Afiliación

Pobbati AV; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA.
Kumar R; Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology, and Research), Singapore 138673.
Rubin BP; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA; Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Hong W; Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology, and Research), Singapore 138673. Electronic address: mcbhwj@imcb.a-star.edu.sg.

Trends Biochem Sci ; 48(5): 450-462, 2023 05.

Article en En | MEDLINE | ID: mdl-36709077

Asunto(s)

Neoplasias; Factores de Transcripción de Dominio TEA; Humanos; Factores de Transcripción/metabolismo; Neoplasias/tratamiento farmacológico; Vía de Señalización Hippo

Palabras clave

Hippo signaling; TEAD; YAP; cancer therapy; drug discovery

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción de Dominio TEA / Neoplasias Límite: Humans Idioma: En Revista: Trends Biochem Sci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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