Design and cytotoxic evaluation via apoptotic and antiproliferative activity for novel 11(4-aminophenylamino)neocryptolepine on hepatocellular and colorectal cancer cells.

Nagy, Esraa Tariq; Ahmed, Abdullah A S; Elmongy, Elshaymaa I; El-Gendy, Saad M; Elmadbouh, Ibrahim; El Sayed, Ibrahim El Tantawy; Abd Eldaim, Mabrouk Attia; El-Gokha, Ahmed A

Nagy, Esraa Tariq; Ahmed, Abdullah A S; Elmongy, Elshaymaa I; El-Gendy, Saad M; Elmadbouh, Ibrahim; El Sayed, Ibrahim El Tantawy; Abd Eldaim, Mabrouk Attia; El-Gokha, Ahmed A.

Afiliación

Nagy ET; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, 32511, Egypt.
Ahmed AAS; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, 32511, Egypt.
Elmongy EI; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, 84428, Saudi Arabia.
El-Gendy SM; Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt.
Elmadbouh I; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Menoufia University, Shebin El Kom, Egypt.
El Sayed IET; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, 32511, Egypt.
Abd Eldaim MA; Department of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, Menoufia University, Sheben Elkom, 32511, Menoufia, Egypt. mabroukattia@vet.menofia.edu.eg.
El-Gokha AA; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, 32511, Egypt.

Apoptosis ; 28(3-4): 653-668, 2023 04.

Article en En | MEDLINE | ID: mdl-36719468

Asunto(s)

Antineoplásicos; Carcinoma Hepatocelular; Neoplasias Colorrectales; Neoplasias Hepáticas; Humanos; Caspasa 3/metabolismo; Carcinoma Hepatocelular/tratamiento farmacológico; Simulación del Acoplamiento Molecular; Neoplasias Hepáticas/tratamiento farmacológico; Neoplasias Hepáticas/genética; Apoptosis; Antineoplásicos/uso terapéutico; Células HCT116; Neoplasias Colorrectales/tratamiento farmacológico; Neoplasias Colorrectales/genética; Proliferación Celular

Palabras clave

APAN; Caspase 3; Ki67; P53; PCNA; VEGF

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_colon_rectum_cancers / 6_digestive_diseases / 6_liver_cancer Asunto principal: Neoplasias Colorrectales / Carcinoma Hepatocelular / Neoplasias Hepáticas / Antineoplásicos Límite: Humans Idioma: En Revista: Apoptosis Año: 2023 Tipo del documento: Article País de afiliación: Egipto

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