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Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions.
Lam, W K Jacky; King, Ann D; Miller, Jacob A; Liu, Zhiwei; Yu, Kelly J; Chua, Melvin L K; Ma, Brigette B Y; Chen, Ming Yuan; Pinsky, Benjamin A; Lou, Pei-Jen; Woo, John K S; Hsu, Wan-Lun; Simon, Julia; Doolan, Denise L; Waterboer, Tim; Hui, Edwin P; Li, Hui; Tsang, Raymond K; Wong, Kenneth C W; Goh, Julian P; Vlantis, Alexander C; Ai, Qi Yong; Wong, Lun M; Abdullah, Victor; Lin, Jin Ching; Chen, Chien-Jen; Pfeiffer, Ruth M; Le, Quynh-Thu; Lee, Anne W M; Ji, Mingfang; Cao, Sumei; Ma, Jun; Chan, Anthony T C; Chan, K C Allen; Hildesheim, Allan.
Afiliación
  • Lam WKJ; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
  • King AD; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Miller JA; Centre for Novostics, Hong Kong Science Park, Hong Kong SAR, China.
  • Liu Z; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Yu KJ; Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Chua MLK; Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Ma BBY; Department of Radiation Oncology, Stanford University, Stanford, CA, USA.
  • Chen MY; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
  • Pinsky BA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
  • Lou PJ; Department of Head and Neck and Thoracic Cancers, Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore.
  • Woo JKS; Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore.
  • Hsu WL; Oncology Academic Programme, Duke-NUS Medical School, Singapore, Singapore.
  • Simon J; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Doolan DL; Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Waterboer T; Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
  • Hui EP; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Center for Precision Medicine of Sun Yat-sen University, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
  • Li H; Department of Pathology, Stanford University, Stanford, CA, USA.
  • Tsang RK; Department of Otolaryngology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.
  • Wong KCW; Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Goh JP; Master Program of Big Data in Biomedicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.
  • Vlantis AC; Data Science Center, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.
  • Ai QY; Infections and Cancer Epidemiology, Infection, Inflammation and Cancer Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Wong LM; Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Abdullah V; Infections and Cancer Epidemiology, Infection, Inflammation and Cancer Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lin JC; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Chen CJ; Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Pfeiffer RM; Department of Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China.
  • Le QT; Department of Otolaryngology-Head and Neck Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Lee AWM; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Ji M; Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Cao S; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Ma J; Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Chan ATC; Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
  • Chan KCA; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
  • Hildesheim A; Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
J Natl Cancer Inst ; 115(4): 355-364, 2023 04 11.
Article en En | MEDLINE | ID: mdl-36723440
ABSTRACT
A meeting of experts was held in November 2021 to review and discuss available data on performance of Epstein-Barr virus (EBV)-based approaches to screen for early stage nasopharyngeal carcinoma (NPC) and methods for the investigation and management of screen-positive individuals. Serum EBV antibody and plasma EBV DNA testing methods were considered. Both approaches were found to have favorable performance characteristics and to be cost-effective in high-risk populations. In addition to endoscopy, use of magnetic resonance imaging (MRI) to investigate screen-positive individuals was found to increase the sensitivity of NPC detection with minimal impact on cost-effectiveness of the screening program.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma / Neoplasias Nasofaríngeas / Infecciones por Virus de Epstein-Barr Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: J Natl Cancer Inst Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma / Neoplasias Nasofaríngeas / Infecciones por Virus de Epstein-Barr Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: J Natl Cancer Inst Año: 2023 Tipo del documento: Article País de afiliación: China