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Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Trefny, Marcel P; Kirchhammer, Nicole; Auf der Maur, Priska; Natoli, Marina; Schmid, Dominic; Germann, Markus; Fernandez Rodriguez, Laura; Herzig, Petra; Lötscher, Jonas; Akrami, Maryam; Stinchcombe, Jane C; Stanczak, Michal A; Zingg, Andreas; Buchi, Melanie; Roux, Julien; Marone, Romina; Don, Leyla; Lardinois, Didier; Wiese, Mark; Jeker, Lukas T; Bentires-Alj, Mohamed; Rossy, Jérémie; Thommen, Daniela S; Griffiths, Gillian M; Läubli, Heinz; Hess, Christoph; Zippelius, Alfred.
Afiliación
  • Trefny MP; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland. marcel.trefny@unibas.ch.
  • Kirchhammer N; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Auf der Maur P; Laboratory of Tumor Heterogeneity, Metastasis and Resistance, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Natoli M; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Schmid D; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Germann M; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Fernandez Rodriguez L; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Herzig P; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Lötscher J; Laboratory of Immunobiology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Akrami M; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Stinchcombe JC; Cambridge Institute for Medical Research, Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Stanczak MA; Laboratory of Cancer Immunotherapy, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Zingg A; Laboratory of Cancer Immunotherapy, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Buchi M; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Roux J; Bioinformatics Core Facility, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Marone R; Swiss Institute of Bioinformatics, Basel, Switzerland.
  • Don L; Laboratory of Molecular Immune Regulation, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Lardinois D; Transplantation Immunology & Nephrology, Basel University Hospital, Basel, Switzerland.
  • Wiese M; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Jeker LT; Department of Surgery, University Hospital Basel, Basel, Switzerland.
  • Bentires-Alj M; Department of Surgery, University Hospital Basel, Basel, Switzerland.
  • Rossy J; Laboratory of Molecular Immune Regulation, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Thommen DS; Transplantation Immunology & Nephrology, Basel University Hospital, Basel, Switzerland.
  • Griffiths GM; Laboratory of Tumor Heterogeneity, Metastasis and Resistance, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Läubli H; Biotechnology Institute Thurgau, University of Konstanz, Kreuzlingen, Switzerland.
  • Hess C; Laboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.
  • Zippelius A; Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Nat Commun ; 14(1): 86, 2023 02 02.
Article en En | MEDLINE | ID: mdl-36732507

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Agotamiento de Células T / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Agotamiento de Células T / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Suiza
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