Pueraria protein extract inhibits melanogenesis and promotes melanoma cell apoptosis through the regulation of MITF and mitochondrial­related pathways.

Zhao, Yuchu; Yu, Shiting; Wang, Yue; Chen, Yanyan; Chen, Jingjing; Wang, Jiawen; Liu, Meichen; Wang, Siming

Pueraria protein extract inhibits melanogenesis and promotes melanoma cell apoptosis through the regulation of MITF and mitochondrialrelated pathways.

Zhao, Yuchu; Yu, Shiting; Wang, Yue; Chen, Yanyan; Chen, Jingjing; Wang, Jiawen; Liu, Meichen; Wang, Siming.

Afiliación

Zhao Y; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Yu S; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Wang Y; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Chen Y; College of Pharmacy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Chen J; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Wang J; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Liu M; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.
Wang S; Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Northeast Asian Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin 130117, P.R. China.

Mol Med Rep ; 27(3)2023 Mar.

Article en En | MEDLINE | ID: mdl-36734267

Asunto(s)

Melanoma Experimental; Pueraria; Animales; Adenosina Trifosfato; Apoptosis; Línea Celular Tumoral; Melaninas; Melanoma Experimental/metabolismo; Factor de Transcripción Asociado a Microftalmía/genética; Factor de Transcripción Asociado a Microftalmía/metabolismo; Mitocondrias/metabolismo; Monofenol Monooxigenasa/metabolismo; Ratones

Palabras clave

Pueraria Lobata protein; apoptosis; melanogenesis; microphthalmia-associated transcription factor; mitochondrial membrane potential

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_malignant_skin_melanoma Asunto principal: Melanoma Experimental / Pueraria Límite: Animals Idioma: En Revista: Mol Med Rep Año: 2023 Tipo del documento: Article

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