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Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer.
Adams, Clare M; Mitra, Ramkrishna; Xiao, Youcai; Michener, Peter; Palazzo, Juan; Chao, Allen; Gour, Jitendra; Cassel, Joel; Salvino, Joseph M; Eischen, Christine M.
Afiliación
  • Adams CM; Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Mitra R; Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Xiao Y; The Wistar Institute, Philadelphia, Pennsylvania.
  • Michener P; Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Palazzo J; Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Chao A; The Wistar Institute, Philadelphia, Pennsylvania.
  • Gour J; The Wistar Institute, Philadelphia, Pennsylvania.
  • Cassel J; The Wistar Institute, Philadelphia, Pennsylvania.
  • Salvino JM; The Wistar Institute, Philadelphia, Pennsylvania.
  • Eischen CM; Department of Pharmacology, Physiology, and Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Cancer Discov ; 13(5): 1210-1229, 2023 05 04.
Article en En | MEDLINE | ID: mdl-36734633
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-mdm2 / Neoplasias de la Mama Triple Negativas / Quimera Dirigida a la Proteólisis Límite: Animals / Female / Humans Idioma: En Revista: Cancer Discov Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-mdm2 / Neoplasias de la Mama Triple Negativas / Quimera Dirigida a la Proteólisis Límite: Animals / Female / Humans Idioma: En Revista: Cancer Discov Año: 2023 Tipo del documento: Article