[Angiogenesis and pulmonary fibrosis].
Zhonghua Jie He He Hu Xi Za Zhi
; 46(2): 197-202, 2023 Feb 12.
Article
en Zh
| MEDLINE
| ID: mdl-36740384
ABSTRACT
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and irreversible lung interstitial disease characterized by repeated damage and accompanied by fibrotic repair, which ultimately leads to structural disorder and destruction of lung tissue, resulting in honeycomb lung. The exact pathogenesis of IPF has not been fully elucidated, and among the many mechanisms, angiogenesis may also be one of the initiating factors of IPF. Chronic, progressive microvascular remodeling disorder has been proved to exist in IPF. This article reviewed the relationship between angiogenesis and development of pulmonary fibrosis in terms of inducement, regulatory factors, regulatory mechanisms, generate rules and therapeutic targets.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Pulmonares Intersticiales
/
Fibrosis Pulmonar Idiopática
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Jie He He Hu Xi Za Zhi
Año:
2023
Tipo del documento:
Article
País de afiliación:
China