FAK loss reduces BRAF<sup>V600E</sup>-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation.

Gao, Chenxi; Ge, Huaibin; Kuan, Shih-Fan; Cai, Chunhui; Lu, Xinghua; Esni, Farzad; Schoen, Robert; Wang, Jing; Chu, Edward; Hu, Jing

FAK loss reduces BRAF^V600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation.

Gao, Chenxi; Ge, Huaibin; Kuan, Shih-Fan; Cai, Chunhui; Lu, Xinghua; Esni, Farzad; Schoen, Robert; Wang, Jing; Chu, Edward; Hu, Jing.

Afiliación

Gao C; University of Pittsburgh.
Ge H; University of Pittsburgh.
Kuan SF; University of Pittsburgh.
Cai C; University of Pittsburgh.
Lu X; University of Pittsburgh.
Esni F; University of Pittsburgh.
Schoen R; University of Pittsburgh.
Wang J; UPMC Hillman Cancer Center/University of Pittsburgh.
Chu E; Albert Einstein Cancer Center.
Hu J; University of pittsburgh.

Res Sq ; 2024 Jan 05.

Article en En | MEDLINE | ID: mdl-36778401

Palabras clave

BRAF mutation; EGFR; ERK; FAK; carcinogenesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Res Sq Año: 2024 Tipo del documento: Article