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Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.
Hicks, Kevin G; Cluntun, Ahmad A; Schubert, Heidi L; Hackett, Sean R; Berg, Jordan A; Leonard, Paul G; Ajalla Aleixo, Mariana A; Zhou, Youjia; Bott, Alex J; Salvatore, Sonia R; Chang, Fei; Blevins, Aubrie; Barta, Paige; Tilley, Samantha; Leifer, Aaron; Guzman, Andrea; Arok, Ajak; Fogarty, Sarah; Winter, Jacob M; Ahn, Hee-Chul; Allen, Karen N; Block, Samuel; Cardoso, Iara A; Ding, Jianping; Dreveny, Ingrid; Gasper, William C; Ho, Quinn; Matsuura, Atsushi; Palladino, Michael J; Prajapati, Sabin; Sun, Pengkai; Tittmann, Kai; Tolan, Dean R; Unterlass, Judith; VanDemark, Andrew P; Vander Heiden, Matthew G; Webb, Bradley A; Yun, Cai-Hong; Zhao, Pengkai; Wang, Bei; Schopfer, Francisco J; Hill, Christopher P; Nonato, Maria Cristina; Muller, Florian L; Cox, James E; Rutter, Jared.
Afiliación
  • Hicks KG; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Cluntun AA; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Schubert HL; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Hackett SR; Calico Life Sciences LLC, South San Francisco, CA, USA.
  • Berg JA; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Leonard PG; Core for Biomolecular Structure and Function, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ajalla Aleixo MA; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhou Y; Laboratório de Cristalografia de Proteinas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
  • Bott AJ; School of Computing, University of Utah, Salt Lake City, UT, USA.
  • Salvatore SR; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA.
  • Chang F; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Blevins A; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Barta P; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Tilley S; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Leifer A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Guzman A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Arok A; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Fogarty S; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Winter JM; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Ahn HC; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Allen KN; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Block S; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Cardoso IA; Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, The Republic of Korea.
  • Ding J; Department of Chemistry, Boston University, Boston, MA, USA.
  • Dreveny I; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Gasper WC; Laboratório de Cristalografia de Proteinas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
  • Ho Q; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Shanghai, China.
  • Matsuura A; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK.
  • Palladino MJ; Department of Biology, Boston University, Boston, MA, USA.
  • Prajapati S; Department of Biology, Boston University, Boston, MA, USA.
  • Sun P; Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, The Republic of Korea.
  • Tittmann K; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Tolan DR; Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, University of Göttingen, Göttingen, Germany.
  • Unterlass J; Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
  • VanDemark AP; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Shanghai, China.
  • Vander Heiden MG; Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, University of Göttingen, Göttingen, Germany.
  • Webb BA; Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
  • Yun CH; Department of Biology, Boston University, Boston, MA, USA.
  • Zhao P; Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden.
  • Wang B; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
  • Schopfer FJ; The Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Hill CP; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Nonato MC; Department of Biochemistry, West Virginia University, Morgantown, WV, USA.
  • Muller FL; Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Cox JE; Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
  • Rutter J; School of Computing, University of Utah, Salt Lake City, UT, USA.
Science ; 379(6636): 996-1003, 2023 03 10.
Article en En | MEDLINE | ID: mdl-36893255
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metabolismo de los Hidratos de Carbono / Metaboloma / L-Lactato Deshidrogenasa Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metabolismo de los Hidratos de Carbono / Metaboloma / L-Lactato Deshidrogenasa Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos